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Insulin's other role in diabetes

Insulin's other role in diabetes

作者:晋愀蜓  时间:2019-03-02 06:05:09  人气:

INSULIN itself is the target of the friendly fire from the immune system that causes juvenile-onset diabetes. It has long been known that type 1 diabetes occurs when the immune system mistakenly views insulin-producing cells in the pancreas as foreign and destroys them. But exactly which molecule is the target of this attack has remained uncertain. Now a team led by George Eisenbarth of the University of Colorado Health Sciences Center in Denver has genetically engineered diabetes-prone mice to produce a modified form of the insulin protein. These mice do not develop diabetes,